In any case, with regard to whatever misdeeds have been done in the past, you should engage in disclosure of them and in developing an intention to restrain from them in the future. For a Buddhist practitioner, the usual practices include prostration and recitation of certain mantras such as the one hundred syllable mantra. One of the best methods is to make gifts to poor and sick persons. The giving of donations for education as well as in the medical field is very great work, one of the best ways to gain merit.
--from The Dalai Lama at Harvard: Lectures on the Buddhist Path to Peace